A benediction in American Indian sign language is fun and easy!
Here's how . . .

ENGLISH
And now,
May the Great Spirit
Of all good spirits,
Be with you,
Now, and forever more.

INDIAN SIGN
Medicine Great
All Good medicine,
Sit with us (me, all)
Now, and forever.

NOW.
Bring extended index finger of right hand about 8 inches in front of face,
and without stopping carry it quickly several inches to front,
stopping with a rebound.

MEDICINE. (Meaning: mysterious and unknown).
Hold right hand close to forehead, palm outwards;
index and second fingers separated and ointing up,
others and thumb closed; move hand upwards
while turning from right to left in a siral.

GREAT.
With palms toward each other
bring extended hands out in front of breast;
then separate the hands to right and left.

ALL.
Move right fist hand in horizontal circle from right to left,
breast high.

GOOD (Meaning level with the heart).
Hold the flat right hand back up,
in front of and close to left breast pointing to left.
Move hand briskly well out to front and to right,
keeping it in a horizontal plane.

SIT.
Hold closed right hand in front of body,
eqully advanced, several inches apart, indexes curved,
move hands forward simultaneously

WITH, AND.
Hold fist left hand, back to left, in front.
Bring side of extended right index against center of left palm,
index pointing to the front.

FOREVER.
Place the open right hand, palm towards right side of head, just clear of head.
Then, move it forward and backward twice,
past front and rear of head.